1647101-05-0
Chemical Structure
Cryptosporioptide A
- CAS No.: 1647101-05-0
- Formula:C18H17NO10
- Molecular Weight:407.33
InChIKey: YGKSSBAOCQEETH-CZIOMAOESA-N
SMILES: C[C@@]1([C@]23[C@](C(C4=C(O)C(C(O)=O)=CC=C4O3)=O)([H])[C@@](O)([C@@]1([H])OC(CC(N2)=O)=O)C)O
Biological Activity: Cryptosporioptide A (Compound 3) is a pigment protein tyrosine phosphatase inhibitor derived from the insect-parasitic fungus Cordyceps gracilioides. Cryptosporioptide A inhibits PTP1B, SHP2, CDC25B, LAR and SHP1 enzymes with IC50 of 7.3, 5.7, 7.6, >50, 4.9 μg/mL, respectively[1].
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Cryptosporioptide A | Cryptosporioptide A (Compound 3) is a pigment protein tyrosine phosphatase inhibitor derived from the insect-parasitic fungus Cordyceps gracilioides. Cryptosporioptide A inhibits PTP1B, SHP2, CDC25B, LAR and SHP1 enzymes with IC50 of 7.3, 5.7, 7.6, >50, 4.9 μg/mL, respectively. | |||||||||||||||||||||
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Keywords