169512-56-5
Chemical Structure
RPR-109891
- CAS No.: 169512-56-5
- Formula:C26H45N5O6
- Molecular Weight:523.67
IUPAC Name: (S)-4-(((S)-1-amino-3-cyclohexyl-1-oxopropan-2-yl)amino)-3-(2-(N-ethyl-4-(piperidin-4-yl)butanamido)acetamido)-4-oxobutanoic acid
InChIKey: PWINFPFVCZSLBF-SFTDATJTSA-N
SMILES: O=C(CCCC1CCNCC1)N(CC)CC(N[C@@H](CC(O)=O)C(N[C@H](C(N)=O)CC2CCCCC2)=O)=O
Biological Activity: RPR-109891 is an orally active glycoprotein IIb/IIIa peptide antagonist. RPR-109891 can decrease platelet count and reduce platelet survival time. RPR-109891 can be used for the research of cardiovascular disease, such as myocardial infarction[1][2].
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RPR-109891 | RPR-109891 is an orally active glycoprotein IIb/IIIa peptide antagonist. RPR-109891 can decrease platelet count and reduce platelet survival time. RPR-109891 can be used for the research of cardiovascular disease, such as myocardial infarction. | |||||||||||||||||||||
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- [1]. Weiss DJ, et al. Platelet kinetics in dogs treated with a glycoprotein IIb/IIIa peptide antagonist. Toxicol Pathol. 2000 Mar-Apr;28(2):310-6. [Content Brief]
- [2]. Giugliano RP, et al. First report of an intravenous and oral glycoprotein IIb/IIIa inhibitor (RPR 109891) in patients with recent acute coronary syndromes: results of the TIMI 15A and 15B trials. Am Heart J. 2000 Jul;140(1):81-93. [Content Brief]
Keywords
