171092-39-0
Chemical Structure
Defoslimod
Synonym(s): OM 174
- CAS No.: 171092-39-0
- Formula:C52H100N2O20P2
- Molecular Weight:1135.30
InChIKey: GOWLTLODGKPXMN-MWJFIXGVSA-N
SMILES: O=P(O)(O)O[C@H]([C@@H]([C@H]([C@@H]1O)O)NC(C[C@H](O)CCCCCCCCCCC)=O)O[C@@H]1CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)OP(O)(O)=O)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCC)=O)=O
Biological Activity: Defoslimod (OM 174) is an agonist for TLR4 receptor and acts as an immunomodulator. Defoslimod activates macrophages and dendritic cells, induces cytokines secretion, and exhibits antitumor efficacy in rats[1].
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Defoslimod | Defoslimod (OM 174) is an agonist for TLR4 receptor and acts as an immunomodulator. Defoslimod activates macrophages and dendritic cells, induces cytokines secretion, and exhibits antitumor efficacy in rats. | |||||||||||||||||||||
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Keywords