175414-77-4
Chemical Structure
Voreloxin
Synonym(s): SNS-595; Vosaroxin; AG 7352
- CAS No.: 175414-77-4
- Formula:C18H19N5O4S
- Molecular Weight:401.44
IUPAC Name: 7-((3S,4S)-3-methoxy-4-(methylamino)pyrrolidin-1-yl)-4-oxo-1-(thiazol-2-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
InChIKey: XZAFZXJXZHRNAQ-STQMWFEESA-N
SMILES: O=C(C1=CN(C2=NC=CS2)C3=C(C=CC(N4C[C@H](OC)[C@@H](NC)C4)=N3)C1=O)O
Biological Activity: Voreloxin (SNS-595; Vosaroxin; AG 7352) is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.
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Voreloxin | 99.85% | Voreloxin (SNS-595; Vosaroxin; AG 7352) is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. | ||||||||||||||||||||
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Voreloxin (Standard) | ≥98% | Voreloxin (Standard) is the analytical standard of Voreloxin (HY-10534). This product is intended for research and analytical applications. Voreloxin (SNS-595; Vosaroxin; AG 7352) is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. | ||||||||||||||||||||
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Keywords