175592-65-1
175592-65-1
Chemical Structure
PD 156252
- CAS No.: 175592-65-1
- Formula:C53H69N7O10
- Molecular Weight:964.16
InChIKey: IMUGSKXBYQZCBP-WFAAYPMKSA-N
SMILES: OC([C@H](CC1=CNC2=CC=CC=C12)NC([C@H]([C@@H](C)CC)N(C)C([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](C3C4=CC=CC=C4CCC5=CC=CC=C53)NC(C)=O)=O)=O)=O)=O)=O)=O
Biological Activity: PD 156252 is a hexapeptide that is a highly potent endothelin (ET) antagonist. PD 156252 has enhanced binding affinity for rabbit ETA and rat ETB receptor subtypes with IC50 values of 1.0 and 40 nM, respectively.
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PD 156252 | PD 156252 is a hexapeptide that is a highly potent endothelin (ET) antagonist. PD 156252 has enhanced binding affinity for rabbit ETA and rat ETB receptor subtypes with IC50 values of 1.0 and 40 nM, respectively. | |||||||||||||||||||||
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Keywords
