178420-94-5
Chemical Structure
Di-O-Toluoyl-1,2-dideoxy-D-ribose-6-chloro-7-iodo-7-deazapurine
- CAS No.: 178420-94-5
- Formula:C27H23ClIN3O5
- Molecular Weight:631.85
IUPAC Name: (2R,3S,5R)-5-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate
InChIKey: VWGDWAFUTMNXBM-BHDDXSALSA-N
SMILES: ClC1=NC=NC2=C1C(I)=CN2[C@@H]3O[C@H](COC(C4=CC=C(C)C=C4)=O)[C@@H](OC(C5=CC=C(C)C=C5)=O)C3
Biological Activity: Di-O-Toluoyl-1,2-dideoxy-D-ribose-6-chloro-7-iodo-7-deazapurine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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Di-O-Toluoyl-1,2-dideoxy-D-ribose-6-chloro-7-iodo-7-deazapurine | Di-O-Toluoyl-1,2-dideoxy-D-ribose-6-chloro-7-iodo-7-deazapurine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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