178616-26-7
178616-26-7
Chemical Structure
CFM-2
- CAS No.: 178616-26-7
- Formula:C17H17N3O3
- Molecular Weight:311.34
IUPAC Name: 1-(4-aminophenyl)-7,8-dimethoxy-3,5-dihydro-4H-benzo[d][1,2]diazepin-4-one
InChIKey: MJKADKZSYQWGLL-UHFFFAOYSA-N
SMILES: O=C1NN=C(C2=CC=C(N)C=C2)C3=CC(OC)=C(OC)C=C3C1
Biological Activity: CFM-2 is a potent and selective non-competitive AMPAR antagonist[1]. CFM-2 possesses anticonvulsant activity in various models of seizures[2].
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CFM-2 | 98.13% | CFM-2 is a potent and selective non-competitive AMPAR antagonist. CFM-2 possesses anticonvulsant activity in various models of seizures. | ||||||||||||||||||||
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CFM-2 (Standard) | ≥98% | CFM-2 (Standard) is the analytical standard of CFM-2. This product is intended for research and analytical applications. CFM-2 is a potent and selective non-competitive AMPAR antagonist. CFM-2 possesses anticonvulsant activity in various models of seizures. | ||||||||||||||||||||
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References
- [1]. De Sarro G, et al. Effects of some AMPA receptor antagonists on the development of tolerance in epilepsy-prone rats and in pentylenetetrazole kindled rats. Eur J Pharmacol. 1999 Mar 5;368(2-3):149-59. [Content Brief]
- [2]. Rizzo M, et al. Determination of new 2,3-benzodiazepines in rat plasma using high-performance liquid chromatography with ultraviolet detection. J Chromatogr B Biomed Sci Appl. 1999 Aug 20;731(2):207-15. [Content Brief]
Keywords
