1799788-94-5
1799788-94-5
Chemical Structure
PF-6683324
Synonym(s): Trk-IN-4
- CAS No.: 1799788-94-5
- Formula:C24H23F4N5O4
- Molecular Weight:521.46
IUPAC Name: 2-(((3R,4S)-3-fluoro-1-(2-(4-(trifluoromethoxy)phenyl)acetyl)piperidin-4-yl)oxy)-5-(1-methyl-1H-imidazol-4-yl)nicotinamide
InChIKey: XJIIVPVOGYFVME-QUCCMNQESA-N
SMILES: O=C(N)C1=C(O[C@H]2CCN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C[C@H]2F)N=CC(C4=CN(C)C=N4)=C1
Biological Activity: PF-6683324 (Trk-IN-4) is a potent pan-Trk inhibitor in cell-based assays with IC50s of 1.9 nM, 2.6 nM and 1.1 nM for TrkA, TrkB and TrkC, respectively[1]. Anti-hyperalgesic effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-6683324 | 99.41% | PF-6683324 (Trk-IN-4) is a potent pan-Trk inhibitor in cell-based assays with IC50s of 1.9 nM, 2.6 nM and 1.1 nM for TrkA, TrkB and TrkC, respectively. Anti-hyperalgesic effect. | ||||||||||||||||||||
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Keywords
