1801597-09-0
Chemical Structure
Sparsentan-d5
Synonym(s): RE-021-d5;DARA-a-d5
- CAS No.: 1801597-09-0
- Formula:C32H35D5N4O5S
- Molecular Weight:597.78
IUPAC Name: 4'-((2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl)-N-(4,5-dimethylisoxazol-3-yl)-2'-((ethoxy-d5)methyl)-[1,1'-biphenyl]-2-sulfonamide
InChIKey: WRFHGDPIDHPWIQ-QKLSXCJMSA-N
SMILES: O=C1C2(CCCC2)N=C(N1CC3=CC(COC([2H])([2H])C([2H])([2H])[2H])=C(C4=C(C=CC=C4)S(NC5=NOC(C)=C5C)(=O)=O)C=C3)CCCC
Biological Activity: Sparsentan-d5 is deuterium labeled Sparsentan. Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively[1].
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Sparsentan-d5 | Sparsentan-d5 is deuterium labeled Sparsentan. Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. | |||||||||||||||||||||
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Sparsentan | 99.87% | Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. | ||||||||||||||||||||
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Keywords
