1817735-36-6
Chemical Structure
Pyrene-amido-PEG4-azide
- CAS No.: 1817735-36-6
- Formula:C25H28N4O4
- Molecular Weight:448.51
IUPAC Name: N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-4,6-dihydropyrene-1-carboxamide
InChIKey: XVKZTMTWYFYOEO-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2C3=C1C=CC4=C3C(CC=C4)=CC2)NCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Pyrene-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Pyrene-amido-PEG4-azide | Pyrene-amido-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Pyrene-amido-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords