1817857-35-4
1817857-35-4
Chemical Structure
NH2-methylpropanamide-Exatecan TFA
- CAS No.: 1817857-35-4
- Formula:C30H30F4N4O7
- Molecular Weight:634.58
InChIKey: MSMQTDLIKIFXGT-WXVOAYBSSA-N
SMILES: OC(C(F)(F)F)=O.NC[C@H](C)C(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)=O
Biological Activity: NH2-methylpropanamide-Exatecan TFA is a methylpropanamide-modified Exatecan (HY-13631), which is the common ADC Cytotoxin used in the synthesis of ADC. Exatecan is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research[1].
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NH2-methylpropanamide-Exatecan TFA | 99.80% | NH2-methylpropanamide-Exatecan TFA is a methylpropanamide-modified Exatecan (HY-13631), which is the common ADC Cytotoxin used in the synthesis of ADC. Exatecan is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research. | ||||||||||||||||||||
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References
Keywords
