1831862-88-4

FXR agonist 12 Chemical Structure
1831862-88-4

Chemical Structure

FXR agonist 12

  • CAS No.: 1831862-88-4
  • Formula:C26H44O3
  • Molecular Weight:404.63

InChIKey: WWEUNIQWUULFSV-GVWKVLGTSA-N

SMILES: C[C@@]12[C@]3([H])[C@]([C@@H]([C@@H]([C@]1([H])CCCC2)CC)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCC(O)=O)C

Biological Activity: FXR agonist 12 (Compound C7) is the orally active agonist for FXR. FXR agonist 12 down-regulates bile acid synthesis-related genes, and up-regulates bile acid transport-related genes in HepG2 cells. FXR agonist 12 improves ANIT-induced cholestasis, ameliorates the liver damage and fibrosis in mouse NASH models[1].

Cat. No. Product Name Purity Description Pricing
HY-164799 		FXR agonist 12 FXR agonist 12 (Compound C7) is the orally active agonist for FXR. FXR agonist 12 down-regulates bile acid synthesis-related genes, and up-regulates bile acid transport-related genes in HepG2 cells. FXR agonist 12 improves ANIT-induced cholestasis, ameliorates the liver damage and fibrosis in mouse NASH models.
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