185415-07-0
Chemical Structure
Raloxifene 4-Monomethyl Ether
- CAS No.: 185415-07-0
- Formula:C29H29NO4S
- Molecular Weight:487.61
IUPAC Name: (6-hydroxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone
InChIKey: RPDULJACWWWFGZ-UHFFFAOYSA-N
SMILES: O=C(C1=C(C2=CC=C(OC)C=C2)SC3=CC(O)=CC=C31)C4=CC=C(OCCN5CCCCC5)C=C4
Biological Activity: Raloxifene 4-Monomethyl Ether (Compound 37) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 1 μM and a pIC50 of 6[1].
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Raloxifene 4-Monomethyl Ether | Raloxifene 4-Monomethyl Ether (Compound 37) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 1 μM and a pIC50 of 6. | |||||||||||||||||||||
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Keywords