187162-33-0
Chemical Structure
L 373890
- CAS No.: 187162-33-0
- Formula:C22H30N6O4S
- Molecular Weight:474.58
IUPAC Name: N-((1-carbamimidoylpiperidin-4-yl)methyl)-2-(6-methyl-2-oxo-3-((phenylmethyl)sulfonamido)pyridin-1(2H)-yl)acetamide
InChIKey: HKBQMUGJGVGZIB-UHFFFAOYSA-N
SMILES: O=S(NC1=CC=C(C)N(CC(NCC2CCN(C(N)=N)CC2)=O)C1=O)(CC3=CC=CC=C3)=O
Biological Activity: L 373890 is a selective pyridinone acetamide thrombin inhibitor with a Ki of 0.5 nM. L 373890 shows highly selectivity for thrombin over trypsin (Ki of 570 nM), serine proteases plasmin, tPA, activated protein C, plasma kallikrein and chymotrypsin. L 373890 can be used for thrombosis research[1].
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L 373890 | L 373890 is a selective pyridinone acetamide thrombin inhibitor with a Ki of 0.5 nM. L 373890 shows highly selectivity for thrombin over trypsin (Ki of 570 nM), serine proteases plasmin, tPA, activated protein C, plasma kallikrein and chymotrypsin. L 373890 can be used for thrombosis research. | |||||||||||||||||||||
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Keywords
