187733-72-8
187733-72-8
Chemical Structure
5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine
- CAS No.: 187733-72-8
- Formula:C12H18N2O5
- Molecular Weight:270.28
IUPAC Name: 1-((2R,3R,4R,5R)-5-ethyl-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChIKey: DGCRVZFJVINYLN-TURQNECASA-N
SMILES: O=C(C(C)=C1)NC(N1[C@@H]2O[C@H](CC)[C@@H](O)[C@H]2OC)=O
Biological Activity: 5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine | 5’-Deoxy-5’-iodo-2’-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
