191786-64-8
Chemical Structure
5’-O-DMTr-2’-OMeU-methyl phosphonamidite
- CAS No.: 191786-64-8
- Formula:C38H48N3O8P
- Molecular Weight:705.78
IUPAC Name: 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((diisopropylamino)(methyl)phosphanyl)oxy)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: OMQYBRGCCIXKCN-IFQFNZHASA-N
SMILES: O=C1C=CN([C@H]2[C@H](OC)[C@H](OP(N(C(C)C)C(C)C)C)[C@@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)O2)C(N1)=O
Biological Activity: 5’-O-DMTr-2’-OMeU-methyl phosphonamidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5’-O-DMTr-2’-OMeU-methyl phosphonamidite | 5’-O-DMTr-2’-OMeU-methyl phosphonamidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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