194034-59-8
194034-59-8
Chemical Structure
2′-O-Methyl-2-amino-6-chloropurine riboside
- CAS No.: 194034-59-8
- Formula:C11H14ClN5O4
- Molecular Weight:315.71
IUPAC Name: (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
InChIKey: MDXXTTIZSFJMOD-KQYNXXCUSA-N
SMILES: ClC1=NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3OC
Biological Activity: 6-Chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2′-O-Methyl-2-amino-6-chloropurine riboside | 6-Chloro-9-(2-O-methyl-beta-D-ribofuranosyl)-9H-purin-2-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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