1941168-63-3
Chemical Structure
MC-Sq-Cit-PAB-Gefitinib
- CAS No.: 1941168-63-3
- Formula:C50H61ClFN10O9
- Molecular Weight:1000.53
IUPAC Name: (S)-4-((3-chloro-4-fluorophenyl)amino)-1-(4-(2-(1-((5-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentyl)carbamoyl)cyclobutane-1-carboxamido)-5-ureidopentanamido)benzyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-1-ium
InChIKey: REJVAWZXGMNZAU-KDXMTYKHSA-O
SMILES: COC1=CC2=[N+](CC3=CC=C(NC([C@@H](NC(C4(C(NCCCCCN5C(C=CC5=O)=O)=O)CCC4)=O)CCCNC(N)=O)=O)C=C3)C=NC(NC6=CC=C(F)C(Cl)=C6)=C2C=C1OCCCN7CCOCC7
Biological Activity: MC-Sq-Cit-PAB-Gefitinib is a agent-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.
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MC-Sq-Cit-PAB-Gefitinib | MC-Sq-Cit-PAB-Gefitinib is a agent-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB. | |||||||||||||||||||||
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Keywords
