2009343-14-8
2009343-14-8
Chemical Structure
PHD-1-IN-1
- CAS No.: 2009343-14-8
- Formula:C13H8N4
- Molecular Weight:220.23
IUPAC Name: 4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)benzonitrile
InChIKey: DEYMFBHALUHGST-UHFFFAOYSA-N
SMILES: N#CC1=CC=C(C2=CC=CC3=NC=NN23)C=C1
Biological Activity: PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an "Arg367-out" pocket[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PHD-1-IN-1 | 99.21% | PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an "Arg367-out" pocket. | ||||||||||||||||||||
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References
Keywords
