2035912-43-5
Chemical Structure
LSD1-IN-6
- CAS No.: 2035912-43-5
- Formula:C15H13BrN2O3
- Molecular Weight:349.18
IUPAC Name: (Z)-4-((E)-2-bromo-4,5-dihydroxystyryl)-N'-hydroxybenzimidamide
InChIKey: JDEDYOAMPIVKCF-ZZXKWVIFSA-N
SMILES: OC1=C(O)C=C(Br)C(/C=C/C2=CC=C(/C(N)=N/O)C=C2)=C1
Biological Activity: LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1].
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LSD1-IN-6 | LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. | |||||||||||||||||||||
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Keywords