2042211-13-0
2042211-13-0
Chemical Structure
Mcl1-IN-11
- CAS No.: 2042211-13-0
- Formula:C38H41N3O5S2
- Molecular Weight:683.88
IUPAC Name: N-((3-nitro-4-((2-(phenylthio)ethyl)amino)phenyl)sulfonyl)-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzamide
InChIKey: UQOYPUQPZRJYPK-UHFFFAOYSA-N
SMILES: CC1(C)C2=CC(C)=C(C(C3=CC=C(C(NS(=O)(C4=CC=C(NCCSC5=CC=CC=C5)C([N+]([O-])=O)=C4)=O)=O)C=C3)=C)C=C2C(C)(C)CC1
Biological Activity: Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1].
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Mcl1-IN-11 | Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively. | |||||||||||||||||||||
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References
Keywords
