2065162-16-3
2065162-16-3
Chemical Structure
Rodin-C
- CAS No.: 2065162-16-3
- Formula:C18H17FN6O
- Molecular Weight:352.37
InChIKey: IAZLIDSAUKQXTC-UHFFFAOYSA-N
SMILES: O=C(N1CC2=NN(C)C=C2C1)NC3=NC(C4=CC=C(F)C=C4)=CC=C3N
Biological Activity: Rodin-C is a selective HDAC inhibitor with IC50s of 0.059, 0.18 and 5.39 μM for HDAC1, HDAC2 and HDAC11, respectively, over HDAC3-10. Rodin-C significantly inhibits the HDAC-CoREST complex with low hematological toxicity. Rodin-C can be used for neurologic disorders such as Alzheimer’s disease research[1].
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Rodin-C | Rodin-C is a selective HDAC inhibitor with IC50s of 0.059, 0.18 and 5.39 μM for HDAC1, HDAC2 and HDAC11, respectively, over HDAC3-10. Rodin-C significantly inhibits the HDAC-CoREST complex with low hematological toxicity. Rodin-C can be used for neurologic disorders such as Alzheimer’s disease research. | |||||||||||||||||||||
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References
Keywords
