Rodin-C
Rodin-C is a selective HDAC inhibitor with IC50s of 0.059, 0.18 and 5.39 μM for HDAC1, HDAC2 and HDAC11, respectively, over HDAC3-10. Rodin-C significantly inhibits the HDAC-CoREST complex with low hematological toxicity. Rodin-C can be used for neurologic disorders such as Alzheimer’s disease research.
For research use only. We do not sell to patients.
- CAS No.: 2065162-16-3
- Formula: C18H17FN6O
- Molecular Weight:352.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC1 0.059 μM (IC50) |
HDAC2 0.18 μM (IC50) |
HDAC3 20.2 μM (IC50) |
HDAC4 >30 μM (IC50) |
HDAC5 >30 μM (IC50) |
HDAC6 >30 μM (IC50) |
HDAC7 >30 μM (IC50) |
HDAC8 >30 μM (IC50) |
HDAC9 >30 μM (IC50) |
HDAC10 >30 μM (IC50) |
HDAC11 5.39 μM (IC50) |
Chemical Information
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CAS No. 2065162-16-3
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Molecular Weight 352.37
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Formula C18H17FN6O
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SMILES
O=C(N1CC2=NN(C)C=C2C1)NC3=NC(C4=CC=C(F)C=C4)=CC=C3N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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