2072145-21-0
2072145-21-0
Chemical Structure
5-Iodo-3’-deoxy-3’-fluorouridine
- CAS No.: 2072145-21-0
- Formula:C9H10FIN2O5
- Molecular Weight:372.09
IUPAC Name: 1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione
InChIKey: VSSVVOWJEMFFSE-UAKXSSHOSA-N
SMILES: F[C@H]1[C@@H](O)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO
Biological Activity: 5-Iodo-3’-deoxy-3’-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-Iodo-3’-deoxy-3’-fluorouridine | 5-Iodo-3’-deoxy-3’-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
Keywords
