208584-57-0
208584-57-0
Chemical Structure
D-myo-Inositol-4,5-diphosphate sodium
Synonym(s): Ins(4,5)-P2 sodium; 4,5-IP2 sodium
- CAS. Nr.: 208584-57-0
- Formula:C6H12Na2O12P2
- Molecular Weight:384.08
SMILES: O[C@@H]1[C@H]([C@@H]([C@H]([C@H]([C@H]1O)O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O
Biological Activity: D-myo-Inositol-4,5-diphosphate (sodium) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-4,5-diphosphate (sodium) can open calcium channels and increase intracellular calcium upon binding to its receptor on the endoplasmic reticulum[1][2][3].
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D-myo-Inositol-4,5-diphosphate sodium | D-myo-Inositol-4,5-diphosphate (sodium) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-4,5-diphosphate (sodium) can open calcium channels and increase intracellular calcium upon binding to its receptor on the endoplasmic reticulum. | |||||||||||||||||||||
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References
- [1]. Streb, H., et al., (1983). Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature, 306(5938), 67–69. [Content Brief]
- [2]. Mikoshiba, K., et al., (1993). Structure and function of inositol 1,4,5-trisphosphate receptor. Annals of the New York Academy of Sciences, 707, 178–197. [Content Brief]
- [3]. Exton J. H. (1996). Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annual review of pharmacology and toxicology, 36, 481–509. [Content Brief]
