2089238-18-4
2089238-18-4
Chemical Structure
Golexanolone
Synonym(s): GR3027
- CAS No.: 2089238-18-4
- Formula:C21H31NO2
- Molecular Weight:329.48
IUPAC Name: (3S,5S,8R,9S,10S,13S,14S,E)-3-ethynyl-3-hydroxy-10,13-dimethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-one oxime
InChIKey: FFIBGVYTWNPLPN-BZLGYYABSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@@](O)(CC2)C#C)([H])[C@@]4([H])[C@](CC3)(/C(CC4)=N/O)C
Biological Activity: Golexanolone is a GABAA receptor modulating steroid antagonist. Golexanolone reduces peripheral inflammation and neuroinflammation and improves cognitive and motor function in hyperammonemic rats[1].
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Golexanolone | Golexanolone is a GABAA receptor modulating steroid antagonist. Golexanolone reduces peripheral inflammation and neuroinflammation and improves cognitive and motor function in hyperammonemic rats. | |||||||||||||||||||||
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References
Keywords
