2107273-58-3
Chemical Structure
N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5
- CAS No.: 2107273-58-3
- Formula:C62H100ClN5O18
- Molecular Weight:1238.93
IUPAC Name: 5-((2,5,8,11-tetraoxatridecan-13-yl)oxy)-2-((1E,3E)-5-((E)-5-((14-azido-3,6,9,12-tetraoxatetradecyl)oxy)-3,3-dimethyl-1-(2,5,8,11-tetraoxatridecan-13-yl)indolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-1-(2,5,8,11-tetraoxatridecan-13-yl)-3H-indol-1-ium
InChIKey: PKHNSJLVAZPWTJ-UHFFFAOYSA-M
SMILES: COCCOCCOCCOCCOC1=CC2=C([N+](CCOCCOCCOCCOC)=C(/C=C/C=C/C=C3N(CCOCCOCCOCCOC)C4=C(C=C(OCCOCCOCCOCCOCCN=[N+]=[N-])C=C4)C/3(C)C)C2(C)C)C=C1.[Cl-]
Biological Activity: N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 | N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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