2107273-84-5
Chemical Structure
N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7
- CAS No.: 2107273-84-5
- Formula:C46H62Cl2N8O6
- Molecular Weight:893.94
IUPAC Name: 1-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-2-((E)-2-((Z)-3-(2-((Z)-1-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-3,3-dimethylindolin-2-ylidene)ethylidene)-2-chlorocyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-3H-indol-1-ium chloride
InChIKey: AGTYTVSFKGQCDO-UHFFFAOYSA-M
SMILES: CC1(C)C(/C=C/C2=C(Cl)/C(CCC2)=C\C=C3N(CCOCCOCCOCCN=[N+]=[N-])C4=C(C=CC=C4)C/3(C)C)=[N+](CCOCCOCCOCCN=[N+]=[N-])C5=C1C=CC=C5.[Cl-]
Biological Activity: N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 | N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. N,N'-bis-(azide-PEG3)-chlorocyclohexenyl Cy7 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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