213192-26-8
213192-26-8
Chemical Structure
TBTC
- CAS No.: 213192-26-8
- Formula:C14H21NO2S
- Molecular Weight:267.39
IUPAC Name: methyl 2-amino-6-(tert-butyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
InChIKey: BYFPSGIBNPFZOY-UHFFFAOYSA-N
SMILES: O=C(OC)C1=C(SC2=C1CCC(C2)C(C)(C)C)N
Biological Activity: TBTC is a selective agonist with the activity of improving behavioral deficits in Alzheimer's disease model mice. TBTC can effectively activate the heterodimerization of RXRα with LXRα or PPARγ. TBTC stimulates the expression of apoE, ABCA1, and ABCG1 genes and reduces Aβ content in cells and animal models[1].
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TBTC | 97.22% | TBTC is a selective agonist with the activity of improving behavioral deficits in Alzheimer's disease model mice. TBTC can effectively activate the heterodimerization of RXRα with LXRα or PPARγ. TBTC stimulates the expression of apoE, ABCA1, and ABCG1 genes and reduces Aβ content in cells and animal models. | ||||||||||||||||||||
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References
Keywords
