2159063-12-2
2159063-12-2
Chemical Structure
PD-1/PD-L1-IN-22
- CAS No.: 2159063-12-2
- Formula:C25H26BrClN2O3
- Molecular Weight:517.84
IUPAC Name: N-(2-((4-((2-bromo-[1,1'-biphenyl]-3-yl)methoxy)-5-chloro-2-methoxybenzyl)amino)ethyl)acetamide
InChIKey: AJJOIMGJHLEMBF-UHFFFAOYSA-N
SMILES: O=C(C)NCCNCC1=CC(Cl)=C(C=C1OC)OCC2=CC=CC(C3=CC=CC=C3)=C2Br
Biological Activity: PD-1/PD-L1-IN-22 (Example 2) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-22 blocks PD-1/PD-L1 with the IC50 of 0.732 μM. PD-1/PD-L1-IN-22 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].
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PD-1/PD-L1-IN-22 | PD-1/PD-L1-IN-22 (Example 2) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-22 blocks PD-1/PD-L1 with the IC50 of 0.732 μM. PD-1/PD-L1-IN-22 can be used for the research of cancers, infectious diseases and autoimmune diseases. | |||||||||||||||||||||
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References
Keywords
