2172833-78-0
Chemical Structure
Attenuatumione H
- CAS No.: 2172833-78-0
- Formula:C35H54O7
- Molecular Weight:586.80
IUPAC Name: (3R,6S,8S,9R,10S)-6-((S)-2,3-dihydroxy-3-methylbutyl)-3-hydroxy-10-isobutyryl-2,2,9-trimethyl-8-(3-methylbut-2-en-1-yl)-9-(4-methylpent-3-en-1-yl)-2,3,4,6,7,8,9,10-octahydro-5H-6,10-methanocycloocta[b]pyran-5,11-dione
InChIKey: RZKTYQKXBDPDTA-SXEXIFEOSA-N
SMILES: CC(C)C([C@]12C3=C(C[C@H](C(C)(O3)C)O)C([C@](C1=O)(C[C@@H]([C@@]2(C)CC/C=C(C)/C)C/C=C(C)\C)C[C@H](O)C(C)(O)C)=O)=O
Biological Activity: Attenuatumione H is a polycyclic polyprenylated acylphloroglucinol compound found in the whole plant of Hypericum attenuatum, and it exhibits antitumor activity. Attenuatumione H exerts cytotoxic effects on liver cancer cells and breast cancer cells. Attenuatumione H shows no significant inhibitory effect on LPS-induced NO production in macrophages and displays no significant cytotoxic activity against osteosarcoma cells. Attenuatumione H can be used in cancer research[1].
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Attenuatumione H | Attenuatumione H is a polycyclic polyprenylated acylphloroglucinol compound found in the whole plant of Hypericum attenuatum, and it exhibits antitumor activity. Attenuatumione H exerts cytotoxic effects on liver cancer cells and breast cancer cells. Attenuatumione H shows no significant inhibitory effect on LPS-induced NO production in macrophages and displays no significant cytotoxic activity against osteosarcoma cells. Attenuatumione H can be used in cancer research. | |||||||||||||||||||||
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