2172907-10-5
2172907-10-5
Chemical Structure
AGH-107
- CAS No.: 2172907-10-5
- Formula:C13H12IN3
- Molecular Weight:337.16
InChIKey: JLCILCCDUVFIRF-UHFFFAOYSA-N
SMILES: IC1=CC=C2NC=C(C3=CN=CN3CC)C2=C1
Biological Activity: AGH-107 is a high selective and brain-penetrant agonist of 5-HT7 receptor, with a Ki of 6 nM and EC50 of 19 nM. AGH-107 exhibits high selectivity over related CNS targets, high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures[1].
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AGH-107 | AGH-107 is a high selective and brain-penetrant agonist of 5-HT7 receptor, with a Ki of 6 nM and EC50 of 19 nM. AGH-107 exhibits high selectivity over related CNS targets, high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures. | |||||||||||||||||||||
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References
Keywords
