2177240-89-8
2177240-89-8
Chemical Structure
Ixazomib-d7
Synonym(s): MLN2238-d7
- CAS No.: 2177240-89-8
- Formula:C14H12D7BCl2N2O4
- Molecular Weight:368.07
IUPAC Name: (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-(methyl-d3)butyl-3,4,4,4-d4)boronic acid
InChIKey: MXAYKZJJDUDWDS-WXCJMVLZSA-N
SMILES: [2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])C[C@@H](B(O)O)NC(CNC(C1=C(C=CC(Cl)=C1)Cl)=O)=O
Biological Activity: Ixazomib-d7 is the deuterium labeled Ixazomib (HY-10453). Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM)[1].
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Ixazomib-d7 | Ixazomib-d7 is the deuterium labeled Ixazomib (HY-10453). Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | |||||||||||||||||||||
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Ixazomib (Standard) | ≥98% | Ixazomib (Standard) is the analytical standard of Ixazomib. This product is intended for research and analytical applications. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | ||||||||||||||||||||
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Ixazomib-13C2,15N | Ixazomib-13C2,15N is 13C and 15N labeled Ixazomib. Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | |||||||||||||||||||||
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Ixazomib | 99.30% | Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM). | ||||||||||||||||||||
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References
