2224491-20-5
2224491-20-5
Chemical Structure
SOF-436
- CAS No.: 2224491-20-5
- Formula:C15H13F2NO4S2
- Molecular Weight:373.39
InChIKey: OHRPRMXMZGBDMS-UHFFFAOYSA-N
SMILES: O=S(C1=CC(S(F)(=O)=O)=CC=C1)(NC2=CC(F)=C(C3CC3)C=C2)=O
Biological Activity: SOF-436 is a KRAS inhibitor that inhibits SOS1-mediated KRAS nucleotide exchange (IC50 = 60 μM) and the binding of KRAS to the effector protein RAF. SOF-436 can be used in cancer research[1].
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SOF-436 | SOF-436 is a KRAS inhibitor that inhibits SOS1-mediated KRAS nucleotide exchange (IC50 = 60 μM) and the binding of KRAS to the effector protein RAF. SOF-436 can be used in cancer research. | |||||||||||||||||||||
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References
Keywords
