2228857-32-5
Chemical Structure
Azidoethyl-SS-propionic acid
- CAS No.: 2228857-32-5
- Formula:C5H9N3O2S2
- Molecular Weight:207.27
IUPAC Name: 3-((2-azidoethyl)disulfanyl)propanoic acid
InChIKey: MIOCIBNCOQTVOB-UHFFFAOYSA-N
SMILES: O=C(O)CCSSCCN=[N+]=[N-]
Biological Activity: Azidoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azidoethyl-SS-propionic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Azidoethyl-SS-propionic acid | Azidoethyl-SS-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azidoethyl-SS-propionic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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Keywords