2237925-62-9

DMA-135 hydrochloride Chemical Structure
2237925-62-9

Chemical Structure

DMA-135 hydrochloride

  • CAS No.: 2237925-62-9
  • Formula:C16H18ClN7O
  • Molecular Weight:359.81

IUPAC Name: 3-amino-N-carbamimidoyl-5-(dimethylamino)-6-(phenylethynyl)pyrazine-2-carboxamide hydrochloride

InChIKey: RBMSZKWMVJWPEP-UHFFFAOYSA-N

SMILES: O=C(C1=NC(C#CC2=CC=CC=C2)=C(N(C)C)N=C1N)NC(N)=N.Cl

Biological Activity: DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. DMA-135 hydrochloride binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM). DMA-135 hydrochloride has no significant toxicity in cell-based studies[1].

Cat. No. Product Name Purity Description Pricing
HY-145932 		DMA-135 hydrochloride 98.04% DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. DMA-135 hydrochloride binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM). DMA-135 hydrochloride has no significant toxicity in cell-based studies.
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