2243882-74-6
2243882-74-6
Chemical Structure
Zedoresertib
Synonym(s): Debio 0123; WEE1-IN-5
- CAS No.: 2243882-74-6
- Formula:C26H28Cl2N6O
- Molecular Weight:511.45
InChIKey: VWHNEYAANMETIA-UHFFFAOYSA-N
SMILES: O=C1C2=CN=C(NC3=CC=C(C4CCN(CC4)C)C(C)=C3)N=C2N(CN1C5=C(Cl)C=CC=C5Cl)C
Biological Activity: Zedoresertib (Debio 0123) is a potent WEE1 inhibitor with an IC50 value of 0.8 nM. Zedoresertib inhibits phospho-CDC2. Zedoresertib abrogates the G2 check point, increasing sensitivity to DNA damaging agents in cancer cells. Zedoresertib can be used for researching anticancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Zedoresertib | 99.85% | Zedoresertib (Debio 0123) is a potent WEE1 inhibitor with an IC50 value of 0.8 nM. Zedoresertib inhibits phospho-CDC2. Zedoresertib abrogates the G2 check point, increasing sensitivity to DNA damaging agents in cancer cells. Zedoresertib can be used for researching anticancer. | ||||||||||||||||||||
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References
Keywords
