2245082-05-5

Sitneprotafib Chemical Structure
2245082-05-5

Chemical Structure

Sitneprotafib

Synonym(s): JAB-3312

  • CAS No.: 2245082-05-5
  • Formula:C21H22ClN7S
  • Molecular Weight:439.96

InChIKey: GKGIGIUNYOFYHZ-LJQANCHMSA-N

SMILES: N[C@H](C(C=CC=N1)=C1C2)C2(CC3)CCN3C(N=C4)=CN=C4SC5=C(Cl)C(N)=NC=C5

Biological Activity: Sitneprotafib (JAB-3312) is an orally effective anticancer phosphatase SHP2 inhibitor (IC50: 1.9 nM) with anti-cancer activity. Sitneprotafib has good tolerability and significantly induced tumor regression in a KYSE-520 mouse xenograft model[1].

Cat. No. Product Name Purity Description Pricing
HY-161952
Sitneprotafib 99.64% Sitneprotafib (JAB-3312) is an orally effective anticancer phosphatase SHP2 inhibitor (IC50: 1.9 nM) with anti-cancer activity. Sitneprotafib has good tolerability and significantly induced tumor regression in a KYSE-520 mouse xenograft model.
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