2307277-93-4
2307277-93-4
Chemical Structure
LRRK2-IN-7
- CAS No.: 2307277-93-4
- Formula:C24H26N6O
- Molecular Weight:414.50
IUPAC Name: (S)-1-(1-(6-((R)-3-(2-hydroxypropan-2-yl)pyrrolidin-1-yl)pyrimidin-4-yl)-1H-indazol-6-yl)spiro[2.2]pentane-1-carbonitrile
InChIKey: JCQABEJXHUSDMF-HOYKHHGWSA-N
SMILES: CC(C)(O)[C@@H]1CCN(C1)C2=NC=NC(N3C4=CC([C@@]5(CC56CC6)C#N)=CC=C4C=N3)=C2
Biological Activity: LRRK2-IN-7 is a potent, selective, and CNS-penetrant LRRK2 kinase inhibitor with an IC50 of 0.9 nM. LRRK2-IN-7 shows >1000-fold selectivity over other kinases, ion channels, and CYP enzymes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LRRK2-IN-7 | 98.03% | LRRK2-IN-7 is a potent, selective, and CNS-penetrant LRRK2 kinase inhibitor with an IC50 of 0.9 nM. LRRK2-IN-7 shows >1000-fold selectivity over other kinases, ion channels, and CYP enzymes. | ||||||||||||||||||||
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References
Keywords
