2309313-01-5
Chemical Structure
Citrulline-specific probe-rhodamine hydrate
- CAS No.: 2309313-01-5
- Formula:C39H37N7O8
- Molecular Weight:731.75
IUPAC Name: 3',6'-bis(dimethylamino)-3-oxo-N-((1-(1-oxo-1-((3-(2-oxoacetyl)phenyl)amino)propan-2-yl)-1H-1,2,3-triazol-4-yl)methyl)-3H-spiro[isobenzofuran-1,9'-xanthene]-5-carboxamide hydrate
InChIKey: CHONNVSIRGWDEB-UHFFFAOYSA-N
SMILES: O=CC(C1=CC(NC(C(C)N2N=NC(CNC(C3=CC=C4C(C(OC45C6=CC=C(N(C)C)C=C6OC7=CC(N(C)C)=CC=C75)=O)=C3)=O)=C2)=O)=CC=C1)=O.O
Biological Activity: Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis[1].
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Citrulline-specific probe-rhodamine hydrate | Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis. | |||||||||||||||||||||
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