2310293-81-1
2310293-81-1
Chemical Structure
Microtubule inhibitor 8
- CAS No.: 2310293-81-1
- Formula:C21H15N3O2S
- Molecular Weight:373.43
InChIKey: SZMUCYJJURIOGS-UHFFFAOYSA-N
SMILES: O=C(C1=CC(SC=N2)=C2N1)NCC3=C(C4=CC5=C(C=CC=C5)O4)C=CC=C3
Biological Activity: Microtubule inhibitor 8 (MP-HJ-1b) is a potent inhibitor of microtubule. Microtubule inhibitor 8 triggers cell death through ferroptosis. Microtubule inhibitor 8 has anti-tumor effect[1][2].
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Microtubule inhibitor 8 | Microtubule inhibitor 8 (MP-HJ-1b) is a potent inhibitor of microtubule. Microtubule inhibitor 8 triggers cell death through ferroptosis. Microtubule inhibitor 8 has anti-tumor effect. | |||||||||||||||||||||
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References
- [1]. Nannan Ning, et al. A Novel Microtubule Inhibitor Overcomes Multidrug Resistance in Tumors. Cancer Res. 2018 Oct 15;78(20):5949-5957. [Content Brief]
- [2]. Nannan Ning, et al. A novel microtubule inhibitor promotes tumor ferroptosis by attenuating SLC7A11/GPX4 signaling. Cell Death Discov. 2023 Dec 13;9(1):453. [Content Brief]
Keywords
