2341796-83-4
2341796-83-4
Chemical Structure
(S,R,S)-AHPC-PEG1-NH2 dihydrochloride
Synonym(s): VH032-PEG1-NH2 dihydrochloride
- CAS No.: 2341796-83-4
- Formula:C26H39Cl2N5O5S
- Molecular Weight:604.59
IUPAC Name: (2S,4R)-1-((S)-2-(2-(2-aminoethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride
InChIKey: DKKLDTGWCBYLGT-YEMZLKFISA-N
SMILES: O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(COCCN)=O.Cl.Cl
Biological Activity: (S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-PEG1-NH2 dihydrochloride can be used to design PROTACs[1].
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(S,R,S)-AHPC-PEG1-NH2 dihydrochloride | (S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-PEG1-NH2 dihydrochloride can be used to design PROTACs. | |||||||||||||||||||||
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References
