2361564-49-8
Chemical Structure
Mito-LND
Synonym(s): Mito-Lonidamine
- CAS No.: 2361564-49-8
- Formula:C43H45BrCl2N3OP
- Molecular Weight:801.62
IUPAC Name: (10-(1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxamido)decyl)triphenylphosphonium bromide
InChIKey: XRSSFQSESARZNG-UHFFFAOYSA-N
SMILES: O=C(NCCCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)C4=NN(CC5=CC=C(Cl)C=C5Cl)C6=C4C=CC=C6.[Br-]
Biological Activity: Mito-LND (Mito-Lonidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation (OXPHOS). Mito-LND inhibits mitochondrial bioenergetics, stimulates the formation of reactive oxygen species, and induces autophagic cell death in lung cancer cells[1].
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Mito-LND | 97.0% | Mito-LND (Mito-Lonidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation (OXPHOS). Mito-LND inhibits mitochondrial bioenergetics, stimulates the formation of reactive oxygen species, and induces autophagic cell death in lung cancer cells. | ||||||||||||||||||||
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Keywords
