2387505-19-1
Chemical Structure
PA2-GNU7
- CAS No.: 2387505-19-1
- Formula:C150H276N50O37
- Molecular Weight:3372.11
SMILES: O=C(NC(CCC(N)=O)C(NC(CCCNC(N)=N)C(NC(CCCCN)C(NC(CC(C)C)C(NC(C)C(NC(C)C(NC(CCCCN)C(NC(CC(C)C)C(NC(C(O)C)C(NC(CO)C(NC(CCCCN)C(NCC(NCC(NCC(NC(CCCNC(N)=N)C(NC(CC(C)C)C(NC(CC(C)C)C(NC(CCCNC(N)=N)C(N1C(CCC1)C(NC(CC(C)C)C(N[C@H](CC(C)C)C(NC(CCC(N)=O)C(N[C@H](CC(C)C)C(NC(CC(C)C)C(N[C@H](CCCCN)C(NC(CCC(N)=O)C(N[C@H](CCCCN)C(N[C@H](CC(C)C)C(N[C@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CO)N
Biological Activity: PA2-GNU7 is an antimicrobial peptide (AMP). PA2-GNU7 exhibits potent antimicrobial activity with minimal inhibitory concentration (MIC) against P. aeruginosa, E. coli, S. typhimurium, S. aureus, and C. albicans are 2 μM, 1 μM, 2 μM, 2 μM, and 8 μM, respectively. PA2-GNU7 rapidly and selectively kills Pseudomonas aeruginosa without affecting other commensal bacteria. PA2-GNU7 significantly improves survival of mice infected with P. aeruginosa. PA2-GNU7 can be used for the research and development of therapeutic agents against MDR Pseudomonas aeruginosa infections[1].
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PA2-GNU7 | PA2-GNU7 is an antimicrobial peptide (AMP). PA2-GNU7 exhibits potent antimicrobial activity with minimal inhibitory concentration (MIC) against P. aeruginosa, E. coli, S. typhimurium, S. aureus, and C. albicans are 2 μM, 1 μM, 2 μM, 2 μM, and 8 μM, respectively. PA2-GNU7 rapidly and selectively kills Pseudomonas aeruginosa without affecting other commensal bacteria. PA2-GNU7 significantly improves survival of mice infected with P. aeruginosa. PA2-GNU7 can be used for the research and development of therapeutic agents against MDR Pseudomonas aeruginosa infections. | |||||||||||||||||||||
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Keywords
