2389988-77-4
Chemical Structure
2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy-3’-fluoroguanosine
- CAS No.: 2389988-77-4
- Formula:C21H22FN5O7
- Molecular Weight:475.43
IUPAC Name: ((2R,3R,4S,5R)-4-acetoxy-5-(2-amino-8-(benzyloxy)-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl acetate
InChIKey: ADTXBERYSVSIRQ-NPNMTCQASA-N
SMILES: O=C1NC(N)=NC2=C1N=C(OCC3=CC=CC=C3)N2[C@@H]4O[C@H](COC(C)=O)[C@@H](F)[C@H]4OC(C)=O
Biological Activity: 2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy-3’-fluoroguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy-3’-fluoroguanosine | 2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy-3’-fluoroguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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