239440-20-1
Chemical Structure
FR183998 free base
- CAS No.: 239440-20-1
- Formula:C17H19Cl2N5O2S
- Molecular Weight:428.34
IUPAC Name: N1-carbamimidoyl-5-(2,5-dichlorothiophen-3-yl)-N3-(2-(dimethylamino)ethyl)isophthalamide
InChIKey: WRLFHDDGGGWFLH-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=C(Cl)SC(Cl)=C2)=CC(C(NCCN(C)C)=O)=C1)NC(N)=N
Biological Activity: FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FR183998 free base | 98.00% | FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively. | ||||||||||||||||||||
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FR183998 free base (Standard) | ≥98% | FR183998 free base (Standard) is the analytical standard of FR183998 free base (HY-100302). This product is intended for research and analytical applications. FR183998 free base is a potent Na+/H+-exchange inhibitor, with IC50s of 0.3 nM, 3.1 nM and 6.5 nM by measurement of pHi change in rat lymphocytes, rat and human platelets, respectively. | ||||||||||||||||||||
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