2447587-73-5
Chemical Structure
VEGFR-2-IN-22
- CAS No.: 2447587-73-5
- Formula:C26H24ClFN4O6
- Molecular Weight:542.94
IUPAC Name: 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1H-1,2,4-triazole-3-carboxamide
InChIKey: URLXPPIGSRGEEZ-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C2=CC=C(F)C(Cl)=C2)C(C3=CC(OC)=C(OC)C(OC)=C3)=N1)NC4=CC=C(OC)C(OC)=C4
Biological Activity: VEGFR-2-IN-22 (Compound 25) is a dual VEGFR-2 and β-tubulin polymerization inhibitor with an IC50 of 19.82 nM against VEGFR-2. VEGFR-2-IN-22 induces apoptosis[1].
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VEGFR-2-IN-22 | VEGFR-2-IN-22 (Compound 25) is a dual VEGFR-2 and β-tubulin polymerization inhibitor with an IC50 of 19.82 nM against VEGFR-2. VEGFR-2-IN-22 induces apoptosis. | |||||||||||||||||||||
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Keywords