2468784-57-6
Chemical Structure
BAY-204
Synonym(s): BRD3727
- CAS No.: 2468784-57-6
- Formula:C29H26F3N5O2
- Molecular Weight:533.54
IUPAC Name: (S)-4,4-difluoro-2-(4-fluorophenyl)-N-(4-(5-methyl-4-oxo-3-(phenylamino)-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl)pyridin-2-yl)butanamide
InChIKey: IKATWWUGCJFQJV-NRFANRHFSA-N
SMILES: O=C1C2=C(NC(C3=CC=NC(NC([C@@H](CC(F)F)C4=CC=C(F)C=C4)=O)=C3)=C2NC5=CC=CC=C5)CCN1C
Biological Activity: BAY-204 (BRD3727) is a potent, ATP-competitive, and selective CSNK1α inhibitor (IC50 = 2 nM at 10 μM ATP; 12 nM at 1 mM ATP). BAY-204 can be used for the study of acute myeloid leukemia (AML)[1][2].
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BAY-204 | 99.94% | BAY-204 (BRD3727) is a potent, ATP-competitive, and selective CSNK1α inhibitor (IC50 = 2 nM at 10 μM ATP; 12 nM at 1 mM ATP). BAY-204 can be used for the study of acute myeloid leukemia (AML). | ||||||||||||||||||||
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Keywords