2495750-19-9

LC kinetic stabilizer-1 Chemical Structure
2495750-19-9

Chemical Structure

LC kinetic stabilizer-1

  • CAS No.: 2495750-19-9
  • Formula:C27H31N5O3
  • Molecular Weight:473.57

IUPAC Name: 1-(3-(1H-imidazol-4-yl)benzyl)-3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)urea

InChIKey: HZXLPUWIDZEPQG-UHFFFAOYSA-N

SMILES: O=C1OC2=CC(N(CC)CC)=CC=C2C(C)=C1CCNC(NCC3=CC(C4=CNC=N4)=CC=C3)=O

Biological Activity: LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer[1].

Cat. No. Product Name Purity Description Pricing
HY-145889 		LC kinetic stabilizer-1 LC kinetic stabilizer-1 (compound 21) is a potent and selective amyloidogenic immunoglobulin light chain kinetic stabilizer with EC50s of 140 and 74.1 nM for WIL-FL* and WIL-FL* T46L/F49Y, respectively. WIL-FL is an amyloidogenic FL LC dimer.
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