2504229-63-2
2504229-63-2
Chemical Structure
MALT1-IN-3
- CAS No.: 2504229-63-2
- Formula:C21H19F3N8O2
- Molecular Weight:472.42
IUPAC Name: (S)-1-(6-(2H-1,2,3-triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl)-3-(5-cyano-4-(cyclopropyl(methoxy)methyl)-6-methylpyridin-3-yl)urea
InChIKey: DDGNZGLBMAPNGD-SFHVURJKSA-N
SMILES: CO[C@@H](C1CC1)C2=C(C#N)C(C)=NC=C2NC(NC3=CN=C(N4N=CC=N4)C(C(F)(F)F)=C3)=O
Biological Activity: MALT1-IN-3 (compound 122) is a potent MALT1 protease inhibitor, with an IC50 of 0.06 μM. MALT1-IN-3 has IC50 of 0.14 and 0.13 μM for human IL6/IL10 in OCI-LY3 cells, respectively[1].
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MALT1-IN-3 | MALT1-IN-3 (compound 122) is a potent MALT1 protease inhibitor, with an IC50 of 0.06 μM. MALT1-IN-3 has IC50 of 0.14 and 0.13 μM for human IL6/IL10 in OCI-LY3 cells, respectively. | |||||||||||||||||||||
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References
Keywords
